United States: The virus causing yellow fever (YF) is believed to have spread to the Region of the Americas since the 17th century and is currently recognized as one of the most threatening mosquito-related infections.
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As reported by the World Health Organization (WHO) on May 16, 2025, the infectious disease is becoming endemic in the tropical areas of 13 countries across the Americas.
During 2025, there were 212 confirmed cases of yellow fever among humans in five Americas countries, leading to 85 deaths (CFR 40%).
Cases of YF were recorded in different Plurinational States of Bolivia, Brazil, Colombia, Ecuador, and Peru.
The WHO stated that the “occurrence of yellow fever outside of the Amazon basin contributes to the overall classification of YF risk in the Americas, especially in endemic countries, as high,” vax-before-travel.com reported.
WHO points out that getting yellow fever vaccination is the top way to stop and control the disease.
WHO is helping countries use YF-VAX in their regular immunization programs and large immunization drives, leading to greater population protection and lower risk of outbreaks.
CDC Urges US Travelers to get vaccinated
It is recommended by the CDC that those in the United States be immunized against yellow fever at least ten days before traveling to affected areas.
The May 2025 vaccination dates for the Yellow Fever (YF) vaccination are found at travel clinics and pharmacies.
“Safety Tips and Ways to Protect Yourself From Yellow Fever“
– Receive the yellow fever vaccine (YF-VAX) at least 10 days before travel to affected areas.
– Wear long-sleeved shirts and long pants when outdoors.
– Yellow fever mosquitoes are daytime biters, especially early morning and late afternoon. Limit exposure during these times.
– Symptoms include fever, chills, headache, muscle pain, nausea, and jaundice (yellowing of skin or eyes).
– Monitor the CDC Travel Health Notices and WHO updates regularly before and during your trip.
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